| Saturday 19 May 2001 |
| Carling Premiership |
| Southampton |
3 (0) |
Arsenal |
2 (1) |
| Sunday 13 May 2001 |
| Carling Premiership |
| Southampton |
2 (2) |
Man Utd |
1 (0) |
| Saturday 5 May 2001 |
| Carling Premiership |
| West Ham |
3 (0) |
Southampton |
0 (0) |
| Tuesday 1 May 2001 |
| Carling Premiership |
| Newcastle |
1 (1) |
Southampton |
1 (0) |
| Saturday 28 April 2001 |
| Carling Premiership |
| Southampton |
0 (0) |
Sunderland |
1 (0) |
| Saturday 21 April 2001 |
| Carling Premiership |
| Aston Villa |
0 (0) |
Southampton |
0 (0) |
| Saturday 14 April 2001 |
| Carling Premiership |
| Chelsea |
1 (1) |
Southampton |
0 (0) |
| Saturday 7 April 2001 |
| Carling Premiership |
| Leeds |
2 (1) |
Southampton |
0 (0) |
| Monday 2 April 2001 |
| Carling Premiership |
| Southampton |
0 (0) |
Ipswich |
3 (1) |
| Saturday 17 March 2001 |
| Carling Premiership |
| Southampton |
1 (0) |
Everton |
0 (0) |
| Saturday 3 March 2001 |
| Carling Premiership |
| Man City |
0 (0) |
Southampton |
1 (0) |
| Saturday 24 February 2001 |
| Carling Premiership |
| Middlesbrough |
0 (0) |
Southampton |
1 (0) |
| Tuesday 20 February 2001 |
| AXA-Sponsored FA Challenge Cup Fifth Round |
| Tranmere |
4 (0) |
Southampton |
3 (3) |
| Saturday 17 February 2001 |
| AXA-Sponsored FA Challenge Cup Fifth Round |
| Southampton |
0 (0) |
Tranmere |
0 (0) |
| Saturday 10 February 2001 |
| Carling Premiership |
| Southampton |
2 (0) |
Bradford |
0 (0) |
| Wednesday 31 January 2001 |
| Carling Premiership |
| Southampton |
1 (0) |
Leicester |
0 (0) |
| Saturday 27 January 2001 |
| AXA-Sponsored FA Challenge Cup Fourth Round |
| Southampton |
3 (1) |
Sheff Wed |
1 (0) |
| Saturday 20 January 2001 |
| Carling Premiership |
| Tottenham |
0 (0) |
Southampton |
0 (0) |
| Saturday 13 January 2001 |
| Carling Premiership |
| Southampton |
0 (0) |
Charlton |
0 (0) |
| Saturday 6 January 2001 |
| AXA-Sponsored FA Challenge Cup Third Round |
| Southampton |
1 (0) |
Sheff Utd |
0 (0) |
| Monday 1 January 2001 |
| Carling Premiership |
| Liverpool |
2 (1) |
Southampton |
1 (1) |
| Saturday 30 December 2000 |
| Carling Premiership |
| Southampton |
1 (0) |
Derby |
0 (0) |
| Wednesday 27 December 2000 |
| Carling Premiership |
| Southampton |
2 (2) |
Tottenham |
0 (0) |
| Friday 22 December 2000 |
| Carling Premiership |
| Coventry |
1 (1) |
Southampton |
1 (0) |
| Saturday 16 December 2000 |
| Carling Premiership |
| Ipswich |
3 (0) |
Southampton |
1 (1) |
| Saturday 9 December 2000 |
| Carling Premiership |
| Southampton |
1 (1) |
Leeds |
0 (0) |
| Saturday 2 December 2000 |
| Carling Premiership |
| Arsenal |
1 (0) |
Southampton |
0 (0) |
| Saturday 25 November 2000 |
| Carling Premiership |
| Southampton |
2 (1) |
West Ham |
3 (2) |
| Saturday 18 November 2000 |
| Carling Premiership |
| Southampton |
2 (2) |
Aston Villa |
0 (0) |
| Saturday 11 November 2000 |
| Carling Premiership |
| Sunderland |
2 (1) |
Southampton |
2 (1) |
| Saturday 4 November 2000 |
| Carling Premiership |
| Southampton |
3 (2) |
Chelsea |
2 (0) |
| Wednesday 1 November 2000 |
| Worthington Cup Third Round |
| Southampton |
0 (0) |
Coventry |
0 (0) |
| Saturday 28 October 2000 |
| Carling Premiership |
| Man Utd |
5 (2) |
Southampton |
0 (0) |
| Monday 23 October 2000 |
| Carling Premiership |
| Southampton |
0 (0) |
Man City |
2 (1) |
| Saturday 14 October 2000 |
| Carling Premiership |
| Everton |
1 (0) |
Southampton |
1 (0) |
| Saturday 30 September 2000 |
| Carling Premiership |
| Southampton |
1 (0) |
Middlesbrough |
3 (2) |
| Tuesday 26 September 2000 |
| Worthington Cup Second Round 2nd Leg |
| Mansfield |
1 (0) |
Southampton |
3 (2) |
| Saturday 23 September 2000 |
| Carling Premiership |
| Bradford |
0 (0) |
Southampton |
1 (1) |
| Wednesday 20 September 2000 |
| Worthington Cup Second Round 1st Leg |
| Southampton |
2 (1) |
Mansfield |
0 (0) |
| Saturday 16 September 2000 |
| Carling Premiership |
| Southampton |
2 (0) |
Newcastle |
0 (0) |
| Saturday 9 September 2000 |
| Carling Premiership |
| Leicester |
1 (0) |
Southampton |
0 (0) |
| Wednesday 6 September 2000 |
| Carling Premiership |
| Charlton |
1 (0) |
Southampton |
1 (0) |
| Saturday 26 August 2000 |
| Carling Premiership |
| Southampton |
3 (0) |
Liverpool |
3 (1) |
| Wednesday 23 August 2000 |
| Carling Premiership |
| Southampton |
1 (0) |
Coventry |
2 (1) |
| Saturday 19 August 2000 |
| Carling Premiership |
| Derby |
2 (1) |
Southampton |
2 (2) |
